BDBM50106865 1-(3-Benzo[1,3]dioxol-5-ylmethyl-3H-imidazol-4-ylmethyl)-4-naphthalen-1-yl-1H-pyrrole-3-carboxylic acid (2-methoxy-ethyl)-methyl-amide::CHEMBL322850

SMILES COCCN(C)C(=O)c1cn(Cc2cncn2Cc2ccc3OCOc3c2)cc1-c1cccc2ccccc12

InChI Key InChIKey=BHBPTTBKKZBFIQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50106865   

LigandPNGBDBM50106865(1-(3-Benzo[1,3]dioxol-5-ylmethyl-3H-imidazol-4-ylm...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of farnesyltransferase activity against K-RasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106865(1-(3-Benzo[1,3]dioxol-5-ylmethyl-3H-imidazol-4-ylm...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Geranylgeranyl transferase type IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50106865(1-(3-Benzo[1,3]dioxol-5-ylmethyl-3H-imidazol-4-ylm...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of farnesyltransferase activity against H-RasMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed