BDBM50108172 6-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-phenoxy]-hexanoic acid::CHEMBL285448
SMILES COc1ccc(OCCCCCC(O)=O)cc1Cc1cnc(N)nc1N
InChI Key InChIKey=IHHWPKHCZVGDIM-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50108172
Affinity DataIC50: 150nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Toxoplasma gondii (Tg)More data for this Ligand-Target Pair