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Found 3 Enz. Inhib. hit(s) with Target = 'Dihydrofolate reductase' and Ligand = 'BDBM50108172'
TargetDihydrofolate reductase(Mycobacterium avium)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108172(6-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50:  150nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from Mycobacterium avium (Ma)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108172(6-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibition of Pneumocystis carinii (Pc) dihydrofolate reductase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50108172(6-[3-(2,4-Diamino-pyrimidin-5-ylmethyl)-4-methoxy-...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of partially purified dihydrofolate reductase (DHFR) from rat liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed