BDBM50110676 CHEMBL280487::okadaic acid
SMILES C[C@@H](C[C@H](O)[C@H]1O[C@@H]2CC[C@@]3(CC[C@@H](O3)\C=C\[C@@H](C)[C@@H]3CC(C)=C[C@@]4(O[C@H](C[C@@](C)(O)C(O)=O)CC[C@H]4O)O3)O[C@H]2[C@H](O)C1=C)[C@H]1O[C@@]2(CCCCO2)CC[C@H]1C
InChI Key InChIKey=QNDVLZJODHBUFM-WFXQOWMNSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 20 hits for monomerid = 50110676
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition activity against protein phosphatase 2A (PP2A), activity taken from literatureMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type R96A by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibitory activity against serine/threonine protein phosphatase 1(PP1)More data for this Ligand-Target Pair
Affinity DataIC50: 3.40nMAssay Description:Tested for inhibition against purified catalytic subunit of protein phosphatase-1 from rabbit skeletal muscleMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: 0.0700nMAssay Description:Tested for inhibition of purified catalytic subunit of protein phosphatase-2A from human erythrocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibitory concentration against Protein phosphatase 1 was determinedMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Concentration required to inhibit the action of protein phosphatase 2AMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Observed inhibition activity against protein phosphatase 1 (PP1)More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 0.450nMAssay Description:Observed inhibition activity against protein phosphatase 2A (PP2A)More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type D220V by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type H248N by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type N124D by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 48nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type E275R by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutants by natural toxins in wild typeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type R221S by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 1.15E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type Y272F by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type D208A by compound was evalutadeMore data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B(Gallus gallus)
University Of California
Curated by ChEMBL
University Of California
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Exogenous inhibition concentration of Serine/threonine protein phosphatase 2A (PP2A)More data for this Ligand-Target Pair
TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
The University Of Newcastle
Curated by ChEMBL
The University Of Newcastle
Curated by ChEMBL
Affinity DataIC50: 78nMAssay Description:Inhibition of Serine/threonine protein phosphatase 1 (PP1) mutant type C127S by compound was evalutadeMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition activity against protein phosphatase 1 (PP1), activity taken from literatureMore data for this Ligand-Target Pair