BDBM50110676 CHEMBL280487::okadaic acid

SMILES C[C@@H](C[C@H](O)[C@H]1O[C@@H]2CC[C@@]3(CC[C@@H](O3)\C=C\[C@@H](C)[C@@H]3CC(C)=C[C@@]4(O[C@H](C[C@@](C)(O)C(O)=O)CC[C@H]4O)O3)O[C@H]2[C@H](O)C1=C)[C@H]1O[C@@]2(CCCCO2)CC[C@H]1C

InChI Key InChIKey=QNDVLZJODHBUFM-WFXQOWMNSA-N

Data  20 IC50

PDB links: 4 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50110676   

TargetSerine/threonine-protein phosphatase PP1-gamma catalytic subunit(Homo sapiens (Human))
Instituto Universitario De Bio-Organica Antonio Gonzalez

Curated by ChEMBL

LigandBDBM50110676(CHEMBL280487 | okadaic acid)Copy SMILESCopy InChI

Affinity DataIC50:  20nMAssay Description:Inhibitory activity against serine/threonine protein phosphatase 1(PP1)More data for this Ligand-Target Pair

Target InfoPDBMMDBNCI pathwayReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

Ligand InfoPurchaseChEBI
CHEMBLKEGGMMDBPC cidPC sidPDBSimilars

In DepthDetails ArticlePubMedMMDB
PDB3D Structure (crystal)
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