BDBM50111322 CHEMBL274335::N,N-Dimethyl-N'-(11-nitro-13H-5,13-diaza-dibenzo[a,i]fluoren-6-yl)-propane-1,3-diamine

SMILES CN(C)CCCNc1nc2ccccc2c2[nH]c3c(ccc4ccc(cc34)[N+]([O-])=O)c12

InChI Key InChIKey=VENNTGMAZAZSJZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50111322   

TargetDNA polymerase I, thermostable(Thermus aquaticus)
National Museum Of Natural History

Curated by ChEMBL
LigandPNGBDBM50111322(CHEMBL274335 | N,N-Dimethyl-N'-(11-nitro-13H-5,13-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Tested for inhibitory activity against Taq DNA polymeraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Museum Of Natural History

Curated by ChEMBL
LigandPNGBDBM50111322(CHEMBL274335 | N,N-Dimethyl-N'-(11-nitro-13H-5,13-...)
Affinity DataIC50:  500nMAssay Description:Tested for inhibitory activity against Telomerase in telomerase repeat amplification protocol (TRAP) assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Museum Of Natural History

Curated by ChEMBL
LigandPNGBDBM50111322(CHEMBL274335 | N,N-Dimethyl-N'-(11-nitro-13H-5,13-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Museum Of Natural History

Curated by ChEMBL
LigandPNGBDBM50111322(CHEMBL274335 | N,N-Dimethyl-N'-(11-nitro-13H-5,13-...)
Affinity DataIC50:  5.01E+8nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
National Museum Of Natural History

Curated by ChEMBL
LigandPNGBDBM50111322(CHEMBL274335 | N,N-Dimethyl-N'-(11-nitro-13H-5,13-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of telomerase (unknown origin) by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed