BDBM50131978 1-Benzyl-pyrrolidine-2-carboxylic acid [1-(benzothiazole-2-carbonyl)-4-guanidino-butyl]-amide; TFA::CHEMBL341148

SMILES NC(=N)NCCC[C@H](NC(=O)[C@@H]1CCCN1Cc1ccccc1)C(=O)c1nc2ccccc2s1

InChI Key InChIKey=NUHSLCPNNDENLB-PMACEKPBSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131978   

TargetSerine protease 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131978(1-Benzyl-pyrrolidine-2-carboxylic acid [1-(benzoth...)
Affinity DataKi:  160nMAssay Description:In vitro inhibition of bovine trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptase beta-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131978(1-Benzyl-pyrrolidine-2-carboxylic acid [1-(benzoth...)
Affinity DataKi:  250nMAssay Description:In vitro inhibition of human Tryptase beta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131978(1-Benzyl-pyrrolidine-2-carboxylic acid [1-(benzoth...)
Affinity DataIC50:  8nMAssay Description:Beta-Trypsin inhibitory activity of compound was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed