BDBM50131988 2-[1-(Benzothiazole-2-carbonyl)-4-guanidino-butylcarbamoyl]-pyrrolidine-1-sulfonic acid methyl ester; TFA::CHEMBL124809

SMILES COS(=O)(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)c1nc2ccccc2s1

InChI Key InChIKey=LIALTYGZACGKAO-KBPBESRZSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131988   

TargetTryptase beta-2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131988(2-[1-(Benzothiazole-2-carbonyl)-4-guanidino-butylc...)
Affinity DataKi:  33nMAssay Description:In vitro inhibition of human Tryptase beta.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131988(2-[1-(Benzothiazole-2-carbonyl)-4-guanidino-butylc...)
Affinity DataKi:  38nMAssay Description:In vitro inhibition of bovine trypsin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTrypsin-3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50131988(2-[1-(Benzothiazole-2-carbonyl)-4-guanidino-butylc...)
Affinity DataIC50:  1nMAssay Description:Beta-Trypsin inhibitory activity of compound was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed