BDBM50135493 5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonic acid (4-acetyl-2-methanesulfonyl-phenyl)-amide::CHEMBL335613

SMILES CC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(F)cc3c2C)c(c1)S(C)(=O)=O

InChI Key InChIKey=MHXGYXIKGYLIMZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135493   

TargetChymotrypsin-C(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50135493(5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibitory activity of the compound against bovin chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymase(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50135493(5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Affinity DataIC50:  82nMAssay Description:In vitro inhibitory activity against human chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50135493(5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonic aci...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibitory activity of the compound against human cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed