BDBM50135494 4-(5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonylamino)-3-methanesulfonyl-benzoic acid methyl ester::CHEMBL129901

SMILES COC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(F)cc3c2C)c(c1)S(C)(=O)=O

InChI Key InChIKey=HQGLOZAWIWWMET-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135494   

TargetChymase(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50135494(4-(5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonyla...)
Affinity DataIC50:  56nMAssay Description:In vitro inhibitory activity against human chymaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50135494(4-(5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonyla...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibitory activity of the compound against bovin chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin G(Homo sapiens (Human))
Toa Eiyo

Curated by ChEMBL
LigandPNGBDBM50135494(4-(5-Fluoro-3-methyl-benzo[b]thiophene-2-sulfonyla...)
Affinity DataIC50: >1.00E+3nMAssay Description:In vitro inhibitory activity of the compound against human cathepsin GMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed