BDBM50166705 2-(1-Benzenesulfonyl-cyclohexyl)-1,4-difluoro-benzene::CHEMBL363802
SMILES Fc1ccc(F)c(c1)C1(CCCCC1)S(=O)(=O)c1ccccc1
InChI Key InChIKey=YLBPZOXTAOZQED-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 50166705
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit APH-1B/Gamma-secretase subunit PEN-2/Nicastrin/Presenilin-1/Presenilin-2(Homo sapiens (Human))
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Merck Sharp & Dohme Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 98nMAssay Description:In vitro inhibition of gamma-secretase as amyloid peptide production in SH-SY5Y cellsMore data for this Ligand-Target Pair