BDBM50168141 CHEMBL3797228

SMILES [H][C@]12Cc3ccc(O)cc3[C@](C)(CCN1CCC(=O)Nc1cccc3ccccc13)[C@H]2C

InChI Key InChIKey=ZBEAXZAFQYRZBS-YJIIWGRFSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50168141   

TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50168141(CHEMBL3797228)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-DPN from rat MOR expressed in EE-HEK293 cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50168141(CHEMBL3797228)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]-DPN from rat DOR expressed in EE-HEK293 cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50168141(CHEMBL3797228)
Affinity DataKi:  800nMAssay Description:Displacement of [3H]-DPN from human KOR expressed in EE-HEK293 cell membranes by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50168141(CHEMBL3797228)
Affinity DataEC50:  5.01E+7nMAssay Description:Agonist activity at MOR in Dunkin-Hartley guinea pig ileum assessed as inhibition of EFS-induced contractions incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50168141(CHEMBL3797228)
Affinity DataEC50:  1.00E+4nMAssay Description:Activity at human KOR expressed in EE-HEK293 cells assessed as pEC50 for effect on (-)U50,488H-induced response (Rvb = 6.2 +/- 0.04 No_unit)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50168141(CHEMBL3797228)
Affinity DataEC50:  7.94E+3nMAssay Description:Antagonist activity at DOR in CD1 mouse vas deferens assessed as pEC50 for DPDPE-induced inhibition of EFS-evoked contractions at 1 uM incubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed