BDBM50169047 (S)-2-(4-Isobutyl-phenyl)-propionic acid::(S)-2-(4-isobutylphenyl)propanoic acid::(S)-ibuprofen::CHEMBL175::DEXIBUPROFEN::IBUPROFEN LYSINE
SMILES CC(C)Cc1ccc(cc1)[C@H](C)C(O)=O
InChI Key InChIKey=HEFNNWSXXWATRW-JTQLQIEISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50169047
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Shanghai Haini Pharmaceutical
Curated by ChEMBL
Shanghai Haini Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of COX1 in human HEL 92.1.7 cells assessed as thromboxane B2 production incubated for 30 mins before arachidonic acid addition measured af...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Shanghai Haini Pharmaceutical
Curated by ChEMBL
Shanghai Haini Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of ovine COX1 by EIAMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Shanghai Haini Pharmaceutical
Curated by ChEMBL
Shanghai Haini Pharmaceutical
Curated by ChEMBL
Affinity DataIC50: 730nMAssay Description:Inhibition of COX2 in LPS-stimulated and PMA-treated human U937 cells assessed as PGE2 production after 15 mins by ELISAMore data for this Ligand-Target Pair