BDBM50169047 (S)-2-(4-Isobutyl-phenyl)-propionic acid::(S)-2-(4-isobutylphenyl)propanoic acid::(S)-ibuprofen::CHEMBL175::DEXIBUPROFEN::IBUPROFEN LYSINE
SMILES CC(C)Cc1ccc(cc1)[C@H](C)C(O)=O
InChI Key InChIKey=HEFNNWSXXWATRW-JTQLQIEISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50169047
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Experimental Botany Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Experimental Botany Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 2.46E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Experimental Botany Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 4.96E+3nMAssay Description:Competitive inhibition of ovine COX-1 assessed as reduction in PGE2 level using 50 nM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Experimental Botany Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: 1.62E+4nMAssay Description:Competitive inhibition of ovine COX-1 assessed as reduction in PGE2 level using 250 nM arachidonic acid as substrate preincubated with enzyme for 5 m...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences
Curated by ChEMBL
Institute Of Experimental Botany Of The Czech Academy Of Sciences
Curated by ChEMBL
Affinity DataIC50: >2.00E+4nMAssay Description:Competitive inhibition of ovine COX-1 assessed as reduction in PGE2 level using 1250 nM arachidonic acid as substrate preincubated with enzyme for 5 ...More data for this Ligand-Target Pair