BDBM50186685 CHEMBL208015::Cbz-Glu(OtBu)-Ala-LeuVSMe

SMILES CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)OC(C)(C)C)NC(=O)OCc1ccccc1)C=CS(C)(=O)=O

InChI Key InChIKey=LRSBIKVQDTUNIU-WWNPGLIZSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50186685   

TargetProteasome subunit beta type-1(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186685(CHEMBL208015 | Cbz-Glu(OtBu)-Ala-LeuVSMe)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186685(CHEMBL208015 | Cbz-Glu(OtBu)-Ala-LeuVSMe)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186685(CHEMBL208015 | Cbz-Glu(OtBu)-Ala-LeuVSMe)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186685(CHEMBL208015 | Cbz-Glu(OtBu)-Ala-LeuVSMe)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of trypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186685(CHEMBL208015 | Cbz-Glu(OtBu)-Ala-LeuVSMe)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed