BDBM50186707 CHEMBL204946::pTosyl-NeopentylAsn-Ser-LeuVSMe

SMILES CC(C)C[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(=O)NCC(C)(C)C)NS(=O)(=O)c1ccc(C)cc1)\C=C\S(C)(=O)=O

InChI Key InChIKey=VAFIHVCGJLLHBQ-QIUANZKBSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50186707   

TargetCathepsin S(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186707(CHEMBL204946 | pTosyl-NeopentylAsn-Ser-LeuVSMe)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of cathepsin SMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186707(CHEMBL204946 | pTosyl-NeopentylAsn-Ser-LeuVSMe)
Affinity DataIC50: >1.50E+5nMAssay Description:Inhibition of cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186707(CHEMBL204946 | pTosyl-NeopentylAsn-Ser-LeuVSMe)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of chymotrypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186707(CHEMBL204946 | pTosyl-NeopentylAsn-Ser-LeuVSMe)
Affinity DataIC50: >4.50E+5nMAssay Description:Inhibition of post glutamyl peptide hydrolase-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
Celera

Curated by ChEMBL
LigandPNGBDBM50186707(CHEMBL204946 | pTosyl-NeopentylAsn-Ser-LeuVSMe)
Affinity DataIC50: >4.50E+5nMAssay Description:Inhibition of trypsin-like proteasome activity of human 20S proteasomeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed