BDBM50192909 CHEMBL3921445::US10329299, Compound 41::US10675286, Compound 41::US11541059, Compound 41::US9775844, Compound 41

SMILES C[C@H](NC(=O)c1c(N)nn2cccnc12)c1cc2cccc(C#Cc3cncs3)c2c(=O)n1-c1ccccc1

InChI Key InChIKey=VLBCDBMQYLNSLY-SFHVURJKSA-N

Data  20 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50192909   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Infinity Pharmaceuticals

US Patent
LigandPNGBDBM50192909(CHEMBL3921445 | US10329299, Compound 41 | US106752...)
Affinity DataIC50:  2.00E+3nMAssay Description:A PI3-Kinase HTRF® assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used spec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Infinity Pharmaceuticals

US Patent
LigandPNGBDBM50192909(CHEMBL3921445 | US10329299, Compound 41 | US106752...)
Affinity DataIC50:  2.00E+3nMAssay Description:A PI3-Kinase HTRF® assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used spec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Infinity Pharmaceuticals

US Patent
LigandPNGBDBM50192909(CHEMBL3921445 | US10329299, Compound 41 | US106752...)
Affinity DataIC50:  2.00E+3nMAssay Description:A PI3-Kinase HTRF® assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used spec...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Infinity Pharmaceuticals

US Patent
LigandPNGBDBM50192909(CHEMBL3921445 | US10329299, Compound 41 | US106752...)
Affinity DataIC50:  3.00E+3nMAssay Description:A PI3-Kinase HTRF® assay kit (cat No. 33-016) purchased from Millipore Corporation was used to screen compounds provided herein. This assay used spec...More data for this Ligand-Target Pair
In DepthDetails US Patent