BDBM50201124 3-(6-(1H-imidazol-1-yl)-4-methyl-1H-benzo[d]imidazol-2-yl)-4-(2-(3-chlorophenyl)-2-hydroxyethylamino)pyridin-2(1H)-one::4-[2-(3-Chloro-phenyl)-2-hydroxy-ethylamino]-3-(6-imidazol-1-yl-4-methyl-1H-benzoimidazol-2-yl)-1H-pyridin-2-one::CHEMBL231306
SMILES Cc1cc(cc2nc([nH]c12)-c1c(NCC(O)c2cccc(Cl)c2)cc[nH]c1=O)-n1ccnc1
InChI Key InChIKey=WASNZPFVELUKFM-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50201124
Affinity DataIC50: <18nMAssay Description:Concentration required to inhibit cytochrome P450 isozyme CYP3A4-BFC in vitro by 50%More data for this Ligand-Target Pair
Affinity DataIC50: <18nMAssay Description:Concentration required to inhibit cytochrome P450 isozyme CYP3A4-BzRes in vitro by 50%More data for this Ligand-Target Pair
Affinity DataIC50: <18nMAssay Description:Concentration required to inhibit Cytochrome P450 1A2 in vitro by 50%More data for this Ligand-Target Pair
Affinity DataIC50: <18nMAssay Description:Concentration required to inhibit Cytochrome P450 2C9 in vitro by 50%More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:Inhibition of human IGF1R expressed in recombinant insect cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Concentration required to inhibit cytochrome P450 isozyme CYP2C19 in vitro by 50%More data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 370nMAssay Description:Inhibition of IGF1R expressed in Sal cellsMore data for this Ligand-Target Pair
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Bristol-Myers Squibb Pharmaceutical Research Institute
Curated by ChEMBL
Affinity DataIC50: 180nMAssay Description:In vitro inhibitory concentration against IGF-1R kinaseMore data for this Ligand-Target Pair