BDBM50208630 CHEMBL3751934

SMILES COc1cccc2c(c[nH]c12)C(=C\c1cccnc1)\C#N

InChI Key InChIKey=NRLRSCFHUUGFDR-MDWZMJQESA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50208630   

TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208630(CHEMBL3751934)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CDK5/p25 using histone H1 as substrate after 30 mins in presence of [gamma-33 P] ATP by liquid scintillation counting...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50208630(CHEMBL3751934)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of GST-tagged human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [g...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Cnrs

Curated by ChEMBL
LigandPNGBDBM50208630(CHEMBL3751934)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate incubated for 30 mins in presence of [gam...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed