BDBM50211976 CHEMBL397323::N-(4-chlorophenyl)-1-(2-(pyridin-4-yl)ethyl)-1H-pyrazole-5-carboxamide
SMILES Clc1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1
InChI Key InChIKey=RDCNEJGSOLCHQO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50211976
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 90nMAssay Description:Displacement of [32P]ATP from human VEGFR2 after 45 minsMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataKi: 110nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataIC50: 97nMAssay Description:Inhibition of VEGFR1 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity
Curated by ChEMBL
Chemical Diversity
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair