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Found 4 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM50211976'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50211976(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)
Affinity DataKi:  90nMAssay Description:Displacement of [32P]ATP from human VEGFR2 after 45 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50211976(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)
Affinity DataKi:  110nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50211976(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)
Affinity DataIC50:  77nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in presence of 2 uM ATP by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Chemical Diversity

Curated by ChEMBL
LigandPNGBDBM50211976(CHEMBL397323 | N-(4-chlorophenyl)-1-(2-(pyridin-4-...)
Affinity DataIC50:  90nMAssay Description:Inhibition of VEGFR2 assessed as inhibition of phosphorylation in human 293 cells by cell-based ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed