BDBM50213021 CHEBI:63621::Fortovase::Invirase::Ro-31-8959::Ro-318959000::Saquinavir::US10806794, Compound Saquinavir
SMILES [H][C@@]12CCCC[C@]1([H])CN(C[C@@H](O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(N)=O)NC(=O)c1ccc3ccccc3n1)[C@@H](C2)C(=O)NC(C)(C)C
InChI Key InChIKey=QWAXKHKRTORLEM-UGJKXSETSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50213021
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.0400nMAssay Description:Inhibition of wild-type HIV1 BH10 protease expressed in Escherichia coli by spectrophotometric assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.138nMAssay Description:Inhibition of HIV1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Inhibition of HIV1 protease expressed in Escherichia coli by fluorometric assayMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.420nMAssay Description:Inhibition of wild type HIV1 protease by competitive bindingMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKi: 0.650nMAssay Description:Binding affinity to wild type HIV1 proteaseMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataIC50: 0.400nMAssay Description:Inhibition of recombinant wild type HIV1 protease assessed as hydrolysis of fluorogenic substrateMore data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKd: 4.10nMAssay Description:Binding affinity to Human immunodeficiency virus 1 protease by SPR biosensor interaction analysis at pH 4.1More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKd: 0.577nMAssay Description:Binding affinity to Human immunodeficiency virus 1 protease by SPR biosensor interaction analysis at pH 7.4More data for this Ligand-Target Pair
TargetProtease(Human immunodeficiency virus 1 (HIV-1))
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Academy Of Sciences Of The Czech Republic
Curated by ChEMBL
Affinity DataKd: 0.637nMAssay Description:Binding affinity to Human immunodeficiency virus 1 protease by SPR biosensor interaction analysis at pH 5.1More data for this Ligand-Target Pair