BDBM50215738 CHEMBL52675

SMILES O[C@@H]1[C@@H](Cc2ccccc2)COc2cc(ccc12)-c1cc(F)ccc1C(O)=O

InChI Key InChIKey=HJCGNZCCPNYWJX-KSFYIVLOSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50215738   

TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50:  5nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50:  5nMAssay Description:Ability to inhibit LTB4-induced chemotaxis of isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50:  12nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50:  3nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50:  600nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50:  240nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50:  240nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophilsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50:  600nMAssay Description:Ability to inhibit LTB4-induced CD11b up-regulation on isolated human neutrophils in whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1/2(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215738(CHEMBL52675)
Affinity DataIC50:  12nMAssay Description:Ability to inhibit LTB4 binding to LTB receptors on isolated human neutrophils.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed