BDBM50216168 CHEMBL132778

SMILES [H][C@@]12CC=C(c3cccnc3)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CCC2=CC(=O)CC[C@]12C

InChI Key InChIKey=GYJZZAJJENTSTP-NHFPKVKZSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50216168   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1/2(Rattus norvegicus)
Kingston University

Curated by ChEMBL
LigandPNGBDBM50216168(CHEMBL132778)
Affinity DataIC50:  1.00E+4nMAssay Description:Compound was tested for the inhibitory activity against Steroid 5-alpha-reductase in ratMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50216168(CHEMBL132778)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of C-terminal His-tagged recombinant human CYP17A1delta19H mutant expressed in Escherichia coli DH5alpha assessed as decrease in progester...More data for this Ligand-Target Pair
TargetSteroid 21-hydroxylase(Homo sapiens (Human))
University Of Kansas

Curated by ChEMBL
LigandPNGBDBM50216168(CHEMBL132778)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of C-terminal His-tagged recombinant human CYP21A2deltaH mutant expressed in Escherichia coli DH5alpha assessed as decrease in progesteron...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed