BDBM50221011 CHEMBL76485

SMILES C[C@H]1COc2c(ccc3c2n1cc(C(O)=O)c3=O)N1CC[C@H](C1)C(C)(C)N

InChI Key InChIKey=SZDPLBCRGFLYCF-NWDGAFQWSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50221011   

TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50221011(CHEMBL76485)
Affinity DataIC50: >2.74E+5nMAssay Description:Inhibitory activity against quinolone resistant gyrase in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50221011(CHEMBL76485)
Affinity DataIC50:  4.03E+5nMAssay Description:Inhibitory activity against mammalian DNA topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50221011(CHEMBL76485)
Affinity DataIC50:  8.61E+3nMAssay Description:Inhibitory activity against wild type gyrase in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed