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Found 3 Enz. Inhib. hit(s) with Target = 'DNA topoisomerase 2-alpha/2-beta' and Ligand = 'BDBM50221011'
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50221011(CHEMBL76485)
Affinity DataIC50:  8.61E+3nMAssay Description:Inhibitory activity against wild type gyrase in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50221011(CHEMBL76485)
Affinity DataIC50: >2.74E+5nMAssay Description:Inhibitory activity against quinolone resistant gyrase in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 2-alpha/2-beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50221011(CHEMBL76485)
Affinity DataIC50:  4.03E+5nMAssay Description:Inhibitory activity against mammalian DNA topoisomerase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed