BDBM50223645 CHEMBL109754

SMILES COc1cc2CCN3c2c(c1)C(=NCC3=O)c1ccccc1

InChI Key InChIKey=NFRVFFWQNXIPGK-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50223645   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50223645(CHEMBL109754)Copy SMILESCopy InChI

Affinity DataIC50:  7.70E+4nMAssay Description:Inhibition of phosphodiesterase 3More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathway
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50223645(CHEMBL109754)Copy SMILESCopy InChI

Affinity DataIC50:  5.20E+4nMAssay Description:Inhibition of Phosphodiesterase 1More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50223645(CHEMBL109754)Copy SMILESCopy InChI

Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of phosphodiesterase 4More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI