BDBM50225504 EHT-0202::Etazolate::SQ-20009

SMILES [#6]-[#6]-[#8]-[#6](=O)-c1cnc2n(-[#6]-[#6])ncc2c1-[#7]\[#7]=[#6](\[#6])-[#6]

InChI Key InChIKey=OPQRBXUBWHDHPQ-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50225504   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50225504(EHT-0202 | Etazolate | SQ-20009)
Affinity DataKi:  1.20E+4nMAssay Description:Binding affinity for low Km cAMP phosphodiesterase PDE III of sheep lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50225504(EHT-0202 | Etazolate | SQ-20009)
Affinity DataKi:  6.00E+4nMAssay Description:Binding affinity for [Ca(2+)]/calmodulin dependent phosphodiesterase PDE 1 of sheep lungMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Sichuan Academy Of Medical Science & Sichuan Provincial People'S Hospital

Curated by ChEMBL
LigandPNGBDBM50225504(EHT-0202 | Etazolate | SQ-20009)
Affinity DataIC50:  390nMAssay Description:Inhibition of PDE4D3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed