BDBM50232675 CHEMBL4100295

SMILES C[C@@]1(CO1)C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)c1cccc(=O)[nH]1

InChI Key InChIKey=QYDASSGXBXGRBS-CKJXQJPGSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50232675   

TargetProteasome subunit beta type-2(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232675(CHEMBL4100295)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of proteasome beta2 in human MOLT4 cell lysate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-10(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232675(CHEMBL4100295)
Affinity DataIC50: >2.50E+5nMAssay Description:Inhibition of MECL1 in human MOLT4 cell lysate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232675(CHEMBL4100295)
Affinity DataIC50:  6.89E+3nMAssay Description:Inhibition of proteasome beta5 in human MOLT4 cell lysate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232675(CHEMBL4100295)
Affinity DataIC50:  4.27E+3nMAssay Description:Inhibition of LMP7 in human MOLT4 cell lysate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232675(CHEMBL4100295)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Beta5 in human 20S immunoproteasome usingAc-WLA-AMC as substrate after 1 hr by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232675(CHEMBL4100295)
Affinity DataIC50:  51nMAssay Description:Inhibition of LMP2 in human MOLT4 cell lysate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-9(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232675(CHEMBL4100295)
Affinity DataIC50:  158nMAssay Description:Inhibition of LMP2 in human 20S immunoproteasome using Ac-PAL-AMC as substrate after 1 hr by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50232675(CHEMBL4100295)
Affinity DataIC50:  4.76E+3nMAssay Description:Inhibition of Beta1 subunit in human 20S proteasome using Ac-nLPnLD-AMC as substrate after 1 hr by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
Kezar Life Sciences

Curated by ChEMBL
LigandPNGBDBM50232675(CHEMBL4100295)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of LMP7 in human 20S immunoproteasome using Ac-ANW-AMC as substrate after 1 hr by fluorescence based microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-1(Homo sapiens (Human))
University Of Kentucky

Curated by ChEMBL
LigandPNGBDBM50232675(CHEMBL4100295)
Affinity DataIC50:  4.64E+4nMAssay Description:Inhibition of proteasome beta1 in human MOLT4 cell lysate after 1 hr by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed