BDBM50232973 CHEMBL254129::CYCLOPAMINE

SMILES C[C@@H]1[C@@H]2NC[C@@H](C)C[C@H]2O[C@]11CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC2=C1C

InChI Key InChIKey=QASFUMOKHFSJGL-LAFRSMQTSA-N

Data  1 KI  11 IC50  1 Kd  1 EC50

PDB links: 3 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232973   

TargetSmoothened homolog(Homo sapiens (Human))
Duke University Medical Center

Curated by ChEMBL
LigandPNGBDBM50232973(CHEMBL254129 | CYCLOPAMINE)
Affinity DataKd:  12.4nMAssay Description:Binding affinity to wild type Smo expressed in U2OS cells by scintillation countingMore data for this Ligand-Target Pair