BDBM50236303 4-(5-cyano-2-(4-fluorophenyl)-1H-indol-3-yl)-N-(trifluoromethylsulfonyl)butanamide::CHEMBL257178
SMILES Fc1ccc(cc1)-c1[nH]c2ccc(cc2c1CCCC(=O)NS(=O)(=O)C(F)(F)F)C#N
InChI Key InChIKey=GVMNNUOOILCXIW-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50236303
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Displacement of europium labeled-human IL8 from human cloned CXCR2 expressed in Sf9 membrane with Galphai3-beta-1-gamma-2 by DELFIA binding assayMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Antagonist activity at human cloned CXCR2 by calcium flux FLIPR assayMore data for this Ligand-Target Pair
TargetC-X-C chemokine receptor type 2(Oryctolagus cuniculus)
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at rabbit CXCR2 by neutrophil chemotaxis assayMore data for this Ligand-Target Pair