BDBM50236897 3-(furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H,7H)-dione::CHEMBL405845::US9180183, Furafylline::furafylline

SMILES Cc1nc2n(Cc3ccco3)c(=O)n(C)c(=O)c2[nH]1

InChI Key InChIKey=KGQZGCIVHYLPBH-UHFFFAOYSA-N

Data  5 KI  28 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50236897   

TargetCytochrome P450 1A2(Homo sapiens (Human))
Korea University Of Science And Technology (Ust)

Curated by ChEMBL
LigandPNGBDBM50236897(3-(furan-2-ylmethyl)-1,8-dimethyl-1H-purine-2,6(3H...)
Affinity DataIC50:  300nMAssay Description:Inhibition of CYP1A2 (unknown origin) using luciferin tagged substrate preincubated for 10 mins before substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed