BDBM50241114 3-(2,4-Difluoro-phenylamino)-6H-dibenzo[b,e]oxepin-11-one::3-(2,4-difluoro-phenylamino)-6,11-dihydro-dibenzo[b,e]oxepin-11-one::CHEMBL376855
SMILES Fc1ccc(Nc2ccc3c(OCc4ccccc4C3=O)c2)c(F)c1
InChI Key InChIKey=JELAHDQPMBHMAI-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50241114
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-UniversitäT
Curated by ChEMBL
Eberhard-Karls-UniversitäT
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Inhibition of p38alpha MAPK (unknown origin) by cell-free enzyme immunosorbent assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-UniversitäT
Curated by ChEMBL
Eberhard-Karls-UniversitäT
Curated by ChEMBL
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of p38alpha MAP kinase in human whole blood assessed as inhibition of LPS-induced TNFalpha release by ELISAMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-UniversitäT
Curated by ChEMBL
Eberhard-Karls-UniversitäT
Curated by ChEMBL
Affinity DataIC50: 239nMAssay Description:Competitive inhibition of p38alpha MAP kinase (unknown origin) in presence of 100 uM ATPMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Eberhard-Karls-UniversitäT
Curated by ChEMBL
Eberhard-Karls-UniversitäT
Curated by ChEMBL
Affinity DataIC50: 239nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair