BDBM50248168 3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)-N-(3,4-difluorophenylsulfonyl)acrylamide::CHEMBL459885

SMILES Cn1cc(\C=C\C(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)cc3Cl)cccc12

InChI Key InChIKey=RJUJTNQHKHWOLR-BJMVGYQFSA-N

Data  6 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50248168   

TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248168(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50:  3.86E+3nMAssay Description:Displacement of radioligand from EP1 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248168(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50:  9.60E+3nMAssay Description:Displacement of radioligand from EP2 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248168(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50:  1.46E+4nMAssay Description:Displacement of radioligand from EP4 receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248168(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50:  23.7nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248168(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataEC50:  26.1nMAssay Description:Antagonist activity at human EP3-2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248168(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50:  11.8nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248168(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50:  1.97E+3nMAssay Description:Displacement of radioligand from FP receptor (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed