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Found 3 Enz. Inhib. hit(s) with Target = 'Prostaglandin E2 receptor EP3 subtype' and Ligand = 'BDBM50248168'
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248168(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50:  11.8nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of normal bufferMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248168(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataIC50:  23.7nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor at 20 uM in presence of 10% human serumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Decode Chemistry

Curated by ChEMBL
LigandPNGBDBM50248168(3-(4-(2,4-dichlorophenoxy)-1-methyl-1H-indol-3-yl)...)
Affinity DataEC50:  26.1nMAssay Description:Antagonist activity at human EP3-2 receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed