BDBM50250948 CHEMBL4099910

SMILES CCc1c(cnc(N)c1-c1ccc(O)cc1)-c1ccc2cn(C)nc2c1

InChI Key InChIKey=NDTDLTOCWHTJKO-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50250948   

TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250948(CHEMBL4099910)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250948(CHEMBL4099910)
Affinity DataIC50: >6.33E+4nMAssay Description:Inhibition of human USP7 using UbA10 as substrate incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250948(CHEMBL4099910)
Affinity DataIC50: >6.33E+4nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed