BDBM50250948 CHEMBL4099910
SMILES CCc1c(cnc(N)c1-c1ccc(O)cc1)-c1ccc2cn(C)nc2c1
InChI Key InChIKey=NDTDLTOCWHTJKO-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50250948
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
Affinity DataIC50: >6.33E+4nMAssay Description:Inhibition of human USP7 using UbA10 as substrate incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataIC50: >6.33E+4nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair