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Found 3 Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 7' and Ligand = 'BDBM50250948'
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250948(CHEMBL4099910)
Affinity DataIC50: >6.33E+4nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250948(CHEMBL4099910)
Affinity DataIC50: >6.33E+4nMAssay Description:Inhibition of human USP7 using UbA10 as substrate incubated for 10 mins by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250948(CHEMBL4099910)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of USP7 in human SJSA cells assessed as increase in ubiquitinated MDM2 level after 16 hrs in presence of MG132 by MSD assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed