BDBM50252405 CHEMBL556353::Pifithrin-Alpha
SMILES Br.Cc1ccc(cc1)C(=O)Cn1c2CCCCc2sc1=N
InChI Key InChIKey=OLTZHXYLLRJLST-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50252405
Affinity DataKi: 4.40nMAssay Description:Inhibition of recombinant CYP1B1 (unknown origin) expressed in supersomes coexpressing NADPH-CYP reductase using 7-ethoxyresorufin as substrate after...More data for this Ligand-Target Pair
Affinity DataIC50: 21nMAssay Description:Inhibition of CYP1B1 in TCDD-exposed human MCF-7 cells using ethoxyresorufin as substrate after 20 mins in presence of NADPH by spectrofluorimetric a...More data for this Ligand-Target Pair
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CYP1A1 in TCDD-exposed human MCF-7 cells using ethoxyresorufin as substrate after 20 mins in presence of NADPH by spectrofluorimetric a...More data for this Ligand-Target Pair