BDBM50253129 CHEMBL4066752
SMILES [H][C@]12CN(C3CCC4(O1)C1Cc5ccc(O)cc5C4(CCN1CC1CC1)C23)C(=O)c1ccccc1
InChI Key InChIKey=KEVICIVUCJDWDH-BTNQZZBKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50253129
Affinity DataKi: 0.154nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium m...More data for this Ligand-Target Pair
Affinity DataKi: 0.274nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.325nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.627nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]U-69,593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 0.540nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair