BDBM50261184 5-((3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)methyl)-N-(2,4,6-trimethoxyphenyl)furan-2-carboxamide::CHEMBL494803

SMILES COc1cc(OC)c(NC(=O)c2ccc(Cc3cc4c(cc3C)C(C)(C)CCC4(C)C)o2)c(OC)c1

InChI Key InChIKey=IPEMCIBPDYCJLO-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50261184   

TargetGonadotropin-releasing hormone receptor(Mus musculus)
Norwegian Medical Cyclotron Centre

Curated by ChEMBL
LigandPNGBDBM50261184(5-((3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphth...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to mouse gonadotropin-releasing hormone receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50261184(5-((3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphth...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity at rat GnRH receptor by competition binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Rattus norvegicus)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50261184(5-((3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphth...)
Affinity DataKi:  3.80nMAssay Description:Binding affinity to rat gonadotropin-releasing hormone receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGonadotropin-releasing hormone receptor(Homo sapiens (Human))
Norwegian Medical Cyclotron Centre

Curated by ChEMBL
LigandPNGBDBM50261184(5-((3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphth...)
Affinity DataKi:  6nMAssay Description:Binding affinity to human gonadotropin-releasing hormone receptor by radioligand displacement assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed