BDBM50264809 2-((4-phenoxyphenylsulfonyl)methyl)thiirane::CHEMBL483857::Thiirane (deuterium), 1-d2::Thiirane, 1::US10357546, SB-3CT

SMILES O=S(=O)(CC1CS1)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=LSONWRHLFZYHIN-UHFFFAOYSA-N

Data  35 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50264809   

Target72 kDa type IV collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  28nMAssay Description:Inhibition of recombinant human MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  400nMAssay Description:Inhibition of recombinant human MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
University Of Notre Dame

Curated by ChEMBL
LigandPNGBDBM50264809(2-((4-phenoxyphenylsulfonyl)methyl)thiirane | CHEM...)
Affinity DataKi:  2.10E+3nMAssay Description:Non-competitive inhibition of MMP8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed