BDBM50274729 CHEMBL4128945
SMILES Cc1cc(O)cc(C)c1C[C@H](N)C(=O)N[C@H](CCCNC(N)=N)C(=O)N[C@@H](Cc1ccc(cc1)C(F)(F)F)C(=O)NCC(N)=O
InChI Key InChIKey=CZDZZPIQDHMNJS-ZRBLBEILSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50274729
Affinity DataEC50: 0.120nMAssay Description:Agonist activity at rat mu-opioid receptor expressed in HEK293 cells co-expressing Rluc2-EPAC-GFP10 biosenser assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
TargetDelta-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit Brussel
Curated by ChEMBL
Vrije Universiteit Brussel
Curated by ChEMBL
Affinity DataEC50: 27nMAssay Description:Agonist activity at rat delta-opioid receptor expressed in HEK293 cells co-expressing Rluc2-EPAC-GFP10 biosenser assessed as inhibition of forskolin-...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Tested for thromboxane antagonist potency (pA2) against U 44619 induced platelet aggregation using human platelet rich plasmaMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Antagonistic potency against thromboxane Thromboxane A2 receptor expressed as inhibition of U 46619-induced platelet aggregation in human platelet ri...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Agonist activity at delta-opioid receptor in mouse vasa deferens assessed as inhibition of electrically induced contractionsMore data for this Ligand-Target Pair
Affinity DataIC50: 0.0700nMAssay Description:Displacement of [125I]-DAMGO from mouse Flag-tagged mu-opioid receptor expressed in HEK293 cell membranes after 60 mins by gamma countingMore data for this Ligand-Target Pair