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Found 3 Enz. Inhib. hit(s) with Target = 'Mu-type opioid receptor' and Ligand = 'BDBM50274729'
TargetMu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50274729(CHEMBL4128945)
Affinity DataIC50:  0.0700nMAssay Description:Displacement of [125I]-DAMGO from mouse Flag-tagged mu-opioid receptor expressed in HEK293 cell membranes after 60 mins by gamma countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50274729(CHEMBL4128945)
Affinity DataIC50:  1.30nMAssay Description:Antagonistic potency against thromboxane Thromboxane A2 receptor expressed as inhibition of U 46619-induced platelet aggregation in human platelet ri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50274729(CHEMBL4128945)
Affinity DataEC50:  0.120nMAssay Description:Agonist activity at rat mu-opioid receptor expressed in HEK293 cells co-expressing Rluc2-EPAC-GFP10 biosenser assessed as inhibition of forskolin-ind...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed