BDBM50276840 CHEMBL4160471

SMILES CCCCN(CC)c1nc(C)nc2n(-c3c(C)cc(C)cc3C)c(=N)sc12

InChI Key InChIKey=WOWDTPMKMJMTLC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276840   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50276840(CHEMBL4160471)
Affinity DataEC50:  1.10nMAssay Description:Antagonist activity at human CRFR1 expressed in HEK293 cells assessed as inhibition of sauvagine-induced cAMP accumulation by measuring sauvagine EC5...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
South Dakota State University

Curated by ChEMBL
LigandPNGBDBM50276840(CHEMBL4160471)
Affinity DataIC50:  170nMAssay Description:Displacement of [125I]-Tyr0-sauvagine from human CRFR1 expressed in HEK293 cell membrane homogenates after 120 mins by gamma counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed