BDBM50277178 CHEMBL4162610

SMILES O=C(C1CCCCC1)N1CC2C(C1)C1CCC2C2CC12

InChI Key InChIKey=WDHVLKXEKRBBSF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50277178   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50277178(CHEMBL4162610)
Affinity DataIC50:  30nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50277178(CHEMBL4162610)
Affinity DataIC50: <100nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mus musculus (mouse))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50277178(CHEMBL4162610)
Affinity DataIC50:  80nMAssay Description:Inhibition of 11beta-HSD1 in CD1 mouse liver microsomes using cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed