BDBM50279934 2-Methoxy-5-(2,3,4-trimethoxy-phenyl)-cyclohepta-2,4,6-trienone::2-methoxy-5-(2,3,4-trimethoxyphenyl)-::CHEMBL79720

SMILES COc1ccc(c(OC)c1OC)-c1ccc(OC)c(=O)cc1

InChI Key InChIKey=QIMGSZURBOTPMW-UHFFFAOYSA-N

Data  1 KI  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50279934   

TargetTubulin alpha-1A chain(Sus scrofa (Pig))
TBA

Curated by ChEMBL
LigandPNGBDBM50279934(2-Methoxy-5-(2,3,4-trimethoxy-phenyl)-cyclohepta-2...)
Affinity DataKi:  1.15E+4nMAssay Description:Compound was evaluated for its ability to inhibit the binding of [3H]-colchicine to tubulin in competitive binding assayMore data for this Ligand-Target Pair
LigandPNGBDBM50279934(2-Methoxy-5-(2,3,4-trimethoxy-phenyl)-cyclohepta-2...)
Affinity DataIC50:  7.50E+3nMAssay Description:In vitro inhibition of purified bovine brain tubulin polymerisation in the absence of microtubule-associated proteins.More data for this Ligand-Target Pair
In DepthDetails
TargetTubulin beta-2B chain(Bos taurus)
TBA

Curated by ChEMBL
LigandPNGBDBM50279934(2-Methoxy-5-(2,3,4-trimethoxy-phenyl)-cyclohepta-2...)
Affinity DataIC50:  2.50E+3nMAssay Description:Compound was evaluated for in vitro inhibitory activity against polymerization of tubulin into microtubules isolated from bovine brain at 1 mg/mL tub...More data for this Ligand-Target Pair