BDBM50290416 CHEMBL293991::{4-[1-(3-Amino-propyl)-1H-indol-4-yl]-pyrimidin-2-yl}-[3-(1,1,2,2-tetrafluoro-ethoxy)-phenyl]-amine

SMILES NCCCn1ccc2c(cccc12)-c1ccnc(Nc2cccc(OC(F)(F)C(F)F)c2)n1

InChI Key InChIKey=HNAIZJDQDDXEGC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50290416   

TargetProtein kinase C alpha type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290416(CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...)
Affinity DataIC50:  180nMAssay Description:Inhibition of protein kinase C alpha.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C delta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290416(CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibition of protein kinase C delta.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290416(CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...)
Affinity DataIC50:  530nMAssay Description:Inhibition of the epidermal growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50290416(CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of protein kinase A.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290416(CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...)
Affinity DataIC50:  350nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People'S Hospital Of Hangzhou

Curated by ChEMBL
LigandPNGBDBM50290416(CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...)
Affinity DataIC50:  347nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290416(CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290416(CHEMBL293991 | {4-[1-(3-Amino-propyl)-1H-indol-4-y...)
Affinity DataIC50:  500nMAssay Description:Inhibition of c-Src-tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article