BDBM50290419 CHEMBL58142::Cyclohexanecarboxylic acid [3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-amide
SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)C1CCCCC1
InChI Key InChIKey=YDUUIKKCZDDRLN-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50290419
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of the epidermal growth factor receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 450nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People'S Hospital Of Hangzhou
Curated by ChEMBL
The First People'S Hospital Of Hangzhou
Curated by ChEMBL
Affinity DataIC50: 447nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
TargetcAMP-dependent protein kinase catalytic subunit alpha/beta/gamma(Homo sapiens (Human))
TBA
Curated by ChEMBL
TBA
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+4nMAssay Description:Inhibition of c-Src-tyrosine kinase.More data for this Ligand-Target Pair