BDBM50290421 CHEMBL55592::N-[3-(4-Pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-isonicotinamide

SMILES O=C(Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1)c1ccncc1

InChI Key InChIKey=MZJIJJIHVGGOAC-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50290421   

TargetProtein kinase C alpha type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290421(CHEMBL55592 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yla...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of protein kinase C alpha.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290421(CHEMBL55592 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yla...)
Affinity DataIC50:  500nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C delta type(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290421(CHEMBL55592 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yla...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of protein kinase C delta.More data for this Ligand-Target Pair
In DepthDetails Article
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290421(CHEMBL55592 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yla...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290421(CHEMBL55592 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yla...)
Affinity DataIC50:  7.80E+4nMAssay Description:Inhibition of c-Src-tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People'S Hospital Of Hangzhou

Curated by ChEMBL
LigandPNGBDBM50290421(CHEMBL55592 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yla...)
Affinity DataIC50:  501nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50290421(CHEMBL55592 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yla...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290421(CHEMBL55592 | N-[3-(4-Pyridin-3-yl-pyrimidin-2-yla...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of the epidermal growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article