BDBM50290430 4-Methyl-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-phenyl]-benzamide::CHEMBL59036

SMILES Cc1ccc(cc1)C(=O)Nc1cccc(Nc2nccc(n2)-c2cccnc2)c1

InChI Key InChIKey=QGIRAHZKAGRURU-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50290430   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290430(4-Methyl-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of the epidermal growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290430(4-Methyl-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of v-Abl tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50290430(4-Methyl-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of protein kinase A.More data for this Ligand-Target Pair
In DepthDetails Article
TargetBreakpoint cluster region protein/Tyrosine-protein kinase ABL1(Homo sapiens (Human))
The First People'S Hospital Of Hangzhou

Curated by ChEMBL
LigandPNGBDBM50290430(4-Methyl-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of BCR-ABL kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290430(4-Methyl-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50:  800nMAssay Description:Inhibition of the platelet-derived growth factor receptor.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50290430(4-Methyl-N-[3-(4-pyridin-3-yl-pyrimidin-2-ylamino)...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of c-Src-tyrosine kinase.More data for this Ligand-Target Pair
In DepthDetails Article